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Cystic fibrosis carriership and tuberculosis: hints toward an evolutionary selective advantage based on data from the Brazilian territory

BACKGROUND: The reason why Cystic Fibrosis (CF) is the most common fatal genetic disease among Caucasians has been incompletely studied. We aimed at deepening the hypothesis that CF carriers have a relative protection against Mycobacterium tuberculosis (Mtb) infection. METHODS: Applying spatial epid...

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Detalles Bibliográficos
Autores principales: Bosch, Lander, Bosch, Barbara, De Boeck, Kris, Nawrot, Tim, Meyts, Isabelle, Vanneste, Dominique, Le Bourlegat, Cleonice Alexandre, Croda, Julio, da Silva Filho, Luiz Vicente Ribeiro Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429554/
https://www.ncbi.nlm.nih.gov/pubmed/28499359
http://dx.doi.org/10.1186/s12879-017-2448-z