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Transcription factor-associated combinatorial epigenetic pattern reveals higher transcriptional activity of TCF7L2-regulated intragenic enhancers

BACKGROUND: Recent studies have suggested that combinations of multiple epigenetic modifications are essential for controlling gene expression. Despite numerous computational approaches have been developed to decipher the combinatorial epigenetic patterns or “epigenetic code”, none of them has expli...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Bonneville, Russell, Li, Tianbao, Jin, Victor X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429574/
https://www.ncbi.nlm.nih.gov/pubmed/28499350
http://dx.doi.org/10.1186/s12864-017-3764-9