Cargando…

The 5′UTR in human adenoviruses: leader diversity in late gene expression

Human adenoviruses (HAdVs) shut down host cellular cap-dependent mRNA translation while initiating the translation of viral late mRNAs in a cap-independent manner. HAdV 5′ untranslated regions (5′UTRs) are crucial for cap-independent initiation, and influence mRNA localization and stability. However...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramke, Mirja, Lee, Jeong Yoon, Dyer, David W., Seto, Donald, Rajaiya, Jaya, Chodosh, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429599/
https://www.ncbi.nlm.nih.gov/pubmed/28377580
http://dx.doi.org/10.1038/s41598-017-00747-y