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20S immunoproteasomes remove formaldehyde-damaged cytoplasmic proteins suppressing caspase-independent cell death

Immunoproteasomes are known for their involvement in antigen presentation. However, their broad tissue presence and other evidence are indicative of nonimmune functions. We examined a role for immunoproteasomes in cellular responses to the endogenous and environmental carcinogen formaldehyde (FA) th...

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Detalles Bibliográficos
Autores principales: Ortega-Atienza, Sara, Krawic, Casey, Watts, Lauren, McCarthy, Caitlin, Luczak, Michal W., Zhitkovich, Anatoly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429636/
https://www.ncbi.nlm.nih.gov/pubmed/28381880
http://dx.doi.org/10.1038/s41598-017-00757-w