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VLP-based vaccine induces immune control of Staphylococcus aureus virulence regulation

Staphylococcus aureus is the leading cause of skin and soft tissue infections (SSTIs) and mounting antibiotic resistance requires innovative treatment strategies. S. aureus uses secreted cyclic autoinducing peptides (AIPs) and the accessory gene regulator (agr) operon to coordinate expression of vir...

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Detalles Bibliográficos
Autores principales: Daly, Seth M., Joyner, Jason A., Triplett, Kathleen D., Elmore, Bradley O., Pokhrel, Srijana, Frietze, Kathryn M., Peabody, David S., Chackerian, Bryce, Hall, Pamela R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429642/
https://www.ncbi.nlm.nih.gov/pubmed/28377579
http://dx.doi.org/10.1038/s41598-017-00753-0