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HMGB1-TLR4-IL23-IL17A axis promotes paraquat-induced acute lung injury by mediating neutrophil infiltration in mice

Paraquat is a poisoning herbicide that primarily targets lung, leading to severe acute lung injury characterized by extensive neutrophil infiltration. However, the mechanisms underlying the neutrophil infiltration is not clear. In this study, we demonstrated the significance of the signaling cascade...

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Detalles Bibliográficos
Autores principales: Yan, Bailing, Chen, Feng, Xu, Lijun, Xing, Jihong, Wang, Xuefu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429653/
https://www.ncbi.nlm.nih.gov/pubmed/28377603
http://dx.doi.org/10.1038/s41598-017-00721-8