Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression

Cancer is a multifactorial disease driven by a combination of genetic and environmental factors. Many cancer driver mutations have been characterised in protein-coding regions of the genome. However, mutations in noncoding regions associated with cancer have been less investigated. G-quadruplex (G4)...

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Detalles Bibliográficos
Autores principales: Zeraati, Mahdi, Moye, Aaron L., Wong, Jason W. H., Perera, Dilmi, Cowley, Mark J., Christ, Daniel U., Bryan, Tracy M., Dinger, Marcel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429658/
https://www.ncbi.nlm.nih.gov/pubmed/28386116
http://dx.doi.org/10.1038/s41598-017-00739-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429658/
https://www.ncbi.nlm.nih.gov/pubmed/28386116
http://dx.doi.org/10.1038/s41598-017-00739-y

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