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Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression
Cancer is a multifactorial disease driven by a combination of genetic and environmental factors. Many cancer driver mutations have been characterised in protein-coding regions of the genome. However, mutations in noncoding regions associated with cancer have been less investigated. G-quadruplex (G4)...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429658/ https://www.ncbi.nlm.nih.gov/pubmed/28386116 http://dx.doi.org/10.1038/s41598-017-00739-y |