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TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes

Potassium channels from prokaryotes and eukaryotes are usually recognized by a typical amino acid sequence TXTGY(F)G representing the ionic selectivity filter. Using a screening approach with ion channel family profiles but without the above motif, we identified a gene in Trypanosoma brucei that exh...

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Detalles Bibliográficos
Autores principales: Steinmann, Michael E., Schmidt, Remo S., Bütikofer, Peter, Mäser, Pascal, Sigel, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429665/
https://www.ncbi.nlm.nih.gov/pubmed/28386071
http://dx.doi.org/10.1038/s41598-017-00752-1