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Recombinant Slit2 Reduces Surgical Brain Injury Induced Blood Brain Barrier Disruption via Robo4 Dependent Rac1 Activation in a Rodent Model
Brain tissue surrounding surgical resection site can be injured inadvertently due to procedures such as incision, retractor stretch, and electrocauterization when performing neurosurgical procedures, which is termed as surgical brain injury (SBI). Blood brain barrier (BBB) disruption due to SBI can...
Autores principales: | Sherchan, Prativa, Huang, Lei, Akyol, Onat, Reis, Cesar, Tang, Jiping, Zhang, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429690/ https://www.ncbi.nlm.nih.gov/pubmed/28389649 http://dx.doi.org/10.1038/s41598-017-00827-z |
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