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Down-regulation of miR-214 reverses erlotinib resistance in non-small-cell lung cancer through up-regulating LHX6 expression

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are standard treatments for advanced non-small-cell lung cancer (NSCLC) patients. However, acquired resistance to EGFR-TKIs is widely detected across the world, and the exact mechanisms have not been fully demonstrated until n...

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Detalles Bibliográficos
Autores principales: Liao, Jinrong, Lin, Jinghui, Lin, Dong, Zou, Changyan, Kurata, Jessica, Lin, Renjang, He, Zhiyong, Su, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429707/
https://www.ncbi.nlm.nih.gov/pubmed/28396596
http://dx.doi.org/10.1038/s41598-017-00901-6