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Human PrimPol activity is enhanced by RPA

Human PrimPol is a primase belonging to the AEP superfamily with the unique ability to synthesize DNA primers de novo, and a non-processive DNA polymerase able to bypass certain DNA lesions. PrimPol facilitates both mitochondrial and nuclear replication fork progression either acting as a convention...

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Detalles Bibliográficos
Autores principales: Martínez-Jiménez, María I., Lahera, Antonio, Blanco, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429719/
https://www.ncbi.nlm.nih.gov/pubmed/28396594
http://dx.doi.org/10.1038/s41598-017-00958-3