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PID1 increases chemotherapy-induced apoptosis in medulloblastoma and glioblastoma cells in a manner that involves NFκB

Phosphotyrosine Interaction Domain containing 1 (PID1; NYGGF4) inhibits growth of medulloblastoma, glioblastoma and atypical teratoid rhabdoid tumor cell lines. PID1 tumor mRNA levels are highly correlated with longer survival in medulloblastoma and glioma patients, suggesting their tumors may have...

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Detalles Bibliográficos
Autores principales: Xu, Jingying, Ren, Xiuhai, Pathania, Anup Singh, Fernandez, G. Esteban, Tran, Anthony, Zhang, Yifu, Moats, Rex A., Shackleford, Gregory M., Erdreich-Epstein, Anat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429784/
https://www.ncbi.nlm.nih.gov/pubmed/28400607
http://dx.doi.org/10.1038/s41598-017-00947-6