Cargando…

A novel 4-arm DNA/RNA Nanoconstruct triggering Rapid Apoptosis of Triple Negative Breast Cancer Cells within 24 hours

Measuring at ~30 nm, a fully customizable holliday junction DNA nanoconstruct, was designed to simultaneously carry three unmodified SiRNA strands for apoptosis gene knockout in cancer cells without any assistance from commercial transfection kits. In brief, a holliday junction structure was intelli...

Descripción completa

Detalles Bibliográficos
Autores principales: Tung, Joline, Tew, Lih Shin, Hsu, Yuan-Man, Khung, Yit Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429792/
https://www.ncbi.nlm.nih.gov/pubmed/28400564
http://dx.doi.org/10.1038/s41598-017-00912-3