Engineered P450 biocatalysts show improved activity and regio-promiscuity in aromatic nitration

Nitroaromatics are among the most important and commonly used chemicals but their production often suffers from multiple unsolved challenges. We have previously described the development of biocatalytic nitration processes driven by an engineered P450 TxtE fusion construct. Herein we report the crea...

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Detalles Bibliográficos
Autores principales: Zuo, Ran, Zhang, Yi, Jiang, Chao, Hackett, John C., Loria, Rosemary, Bruner, Steven D., Ding, Yousong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429796/
https://www.ncbi.nlm.nih.gov/pubmed/28405004
http://dx.doi.org/10.1038/s41598-017-00897-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429796/
https://www.ncbi.nlm.nih.gov/pubmed/28405004
http://dx.doi.org/10.1038/s41598-017-00897-z

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