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Engineered P450 biocatalysts show improved activity and regio-promiscuity in aromatic nitration
Nitroaromatics are among the most important and commonly used chemicals but their production often suffers from multiple unsolved challenges. We have previously described the development of biocatalytic nitration processes driven by an engineered P450 TxtE fusion construct. Herein we report the crea...
Autores principales: | Zuo, Ran, Zhang, Yi, Jiang, Chao, Hackett, John C., Loria, Rosemary, Bruner, Steven D., Ding, Yousong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429796/ https://www.ncbi.nlm.nih.gov/pubmed/28405004 http://dx.doi.org/10.1038/s41598-017-00897-z |
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