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MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff

Mitochondrial dynamics is a fundamental cellular process and recruitment of Drp1 to mitochondria is an essential step in mitochondrial fission. Mff and MIEF1/2 (MiD51/49) serve as key receptors for recruitment of Drp1 to mitochondria in mammals. However, if and how these receptors work together in m...

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Detalles Bibliográficos
Autores principales: Yu, Rong, Liu, Tong, Jin, Shao-Bo, Ning, Chenfei, Lendahl, Urban, Nistér, Monica, Zhao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429825/
https://www.ncbi.nlm.nih.gov/pubmed/28408736
http://dx.doi.org/10.1038/s41598-017-00853-x