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Endothelial and Astrocytic Support by Human Bone Marrow Stem Cell Grafts into Symptomatic ALS Mice towards Blood-Spinal Cord Barrier Repair

Vascular pathology, including blood-CNS barrier (B-CNS-B) damage via endothelial cell (EC) degeneration, is a recently recognized hallmark of Amyotrophic Lateral Sclerosis (ALS) pathogenesis. B-CNS-B repair may be a new therapeutic approach for ALS. This study aimed to determine effects of transplan...

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Detalles Bibliográficos
Autores principales: Garbuzova-Davis, Svitlana, Kurien, Crupa, Thomson, Avery, Falco, Dimitri, Ahmad, Sohaib, Staffetti, Joseph, Steiner, George, Abraham, Sophia, James, Greeshma, Mahendrasah, Ajay, Sanberg, Paul R., Borlongan, Cesario V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429840/
https://www.ncbi.nlm.nih.gov/pubmed/28408761
http://dx.doi.org/10.1038/s41598-017-00993-0