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Endothelial and Astrocytic Support by Human Bone Marrow Stem Cell Grafts into Symptomatic ALS Mice towards Blood-Spinal Cord Barrier Repair
Vascular pathology, including blood-CNS barrier (B-CNS-B) damage via endothelial cell (EC) degeneration, is a recently recognized hallmark of Amyotrophic Lateral Sclerosis (ALS) pathogenesis. B-CNS-B repair may be a new therapeutic approach for ALS. This study aimed to determine effects of transplan...
Autores principales: | Garbuzova-Davis, Svitlana, Kurien, Crupa, Thomson, Avery, Falco, Dimitri, Ahmad, Sohaib, Staffetti, Joseph, Steiner, George, Abraham, Sophia, James, Greeshma, Mahendrasah, Ajay, Sanberg, Paul R., Borlongan, Cesario V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429840/ https://www.ncbi.nlm.nih.gov/pubmed/28408761 http://dx.doi.org/10.1038/s41598-017-00993-0 |
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