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Reduced biological effect of e-cigarette aerosol compared to cigarette smoke evaluated in vitro using normalized nicotine dose and RNA-seq-based toxicogenomics

Electronic cigarettes (e-cigarettes) use has increased globally and could potentially offer a lower risk alternative to cigarette smoking. Here, we assessed the transcriptional response of a primary 3D airway model acutely exposed to e-cigarette aerosol and cigarette (3R4F) smoke. Aerosols were gene...

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Detalles Bibliográficos
Autores principales: Haswell, Linsey E., Baxter, Andrew, Banerjee, Anisha, Verrastro, Ivan, Mushonganono, Jessica, Adamson, Jason, Thorne, David, Gaça, Marianna, Minet, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429854/
https://www.ncbi.nlm.nih.gov/pubmed/28420881
http://dx.doi.org/10.1038/s41598-017-00852-y