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Novel GLP-1 Analog Supaglutide Reduces HFD-Induced Obesity Associated with Increased Ucp-1 in White Adipose Tissue in Mice

GLP-1, an important incretin hormone plays an important role in the regulation of glucose homeostasis. However, the therapeutic use of native GLP-1 is limited due to its short half-life. We recently developed a novel GLP-1 mimetics (supaglutide) by genetically engineering recombinant fusion protein...

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Detalles Bibliográficos
Autores principales: Wan, Yun, Bao, Xi, Huang, Jiabao, Zhang, Xiangyu, Liu, Wenjuan, Cui, Qiaoli, Jiang, Dongdong, Wang, Zhihong, Liu, Rui, Wang, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430033/
https://www.ncbi.nlm.nih.gov/pubmed/28555111
http://dx.doi.org/10.3389/fphys.2017.00294