Cargando…
Novel GLP-1 Analog Supaglutide Reduces HFD-Induced Obesity Associated with Increased Ucp-1 in White Adipose Tissue in Mice
GLP-1, an important incretin hormone plays an important role in the regulation of glucose homeostasis. However, the therapeutic use of native GLP-1 is limited due to its short half-life. We recently developed a novel GLP-1 mimetics (supaglutide) by genetically engineering recombinant fusion protein...
Autores principales: | Wan, Yun, Bao, Xi, Huang, Jiabao, Zhang, Xiangyu, Liu, Wenjuan, Cui, Qiaoli, Jiang, Dongdong, Wang, Zhihong, Liu, Rui, Wang, Qinghua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430033/ https://www.ncbi.nlm.nih.gov/pubmed/28555111 http://dx.doi.org/10.3389/fphys.2017.00294 |
Ejemplares similares
-
Novel GLP-1 Analog Supaglutide Stimulates Insulin Secretion in Mouse and Human Islet Beta-Cells and Improves Glucose Homeostasis in Diabetic Mice
por: Ren, Liwei, et al.
Publicado: (2019) -
Ctnnb1/β-catenin inactivation in UCP1-positive adipocytes augments the browning of white adipose tissue
por: Chen, Na, et al.
Publicado: (2023) -
Acupuncture promotes white adipose tissue browning by inducing UCP1 expression on DIO mice
por: Shen, Weixing, et al.
Publicado: (2014) -
The expression of UCP3 directly correlates to UCP1 abundance in brown adipose tissue
por: Hilse, Karolina E., et al.
Publicado: (2016) -
UCP1 Induction during Recruitment of Brown Adipocytes in White Adipose Tissue Is Dependent on Cyclooxygenase Activity
por: Madsen, Lise, et al.
Publicado: (2010)