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DNA methylation epigenotype and clinical features of NRAS‐mutation(+) colorectal cancer

Sporadic colorectal cancer (CRC) is classified into several molecular subtypes. We previously established two groups of DNA methylation markers through genome‐wide DNA methylation analysis to classify CRC into distinct subgroups: high‐, intermediate‐, and low‐methylation epigenotypes (HME, IME, and...

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Detalles Bibliográficos
Autores principales: Takane, Kiyoko, Akagi, Kiwamu, Fukuyo, Masaki, Yagi, Koichi, Takayama, Tadatoshi, Kaneda, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430106/
https://www.ncbi.nlm.nih.gov/pubmed/28378457
http://dx.doi.org/10.1002/cam4.1061