Validation of a routine two‐sample iohexol plasma clearance assessment of GFR and an evaluation of common endogenous markers in a rat model of CKD

Endogenous markers of kidney function are insensitive to early declines in glomerular filtration rate (GFR) and in rodent models, validated, practical alternatives are unavailable. In this study, we determined GFR by modeling the plasma clearance of two compounds, iohexol and inulin, and compared th...

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Detalles Bibliográficos
Autores principales: Turner, Mandy E., Laverty, Kimberly J., Jeronimo, Paul S., Kaufmann, Martin, Jones, Glenville, White, Christine A., Holden, Rachel M., Adams, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430119/
https://www.ncbi.nlm.nih.gov/pubmed/28483858
http://dx.doi.org/10.14814/phy2.13205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430119/
https://www.ncbi.nlm.nih.gov/pubmed/28483858
http://dx.doi.org/10.14814/phy2.13205

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