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Antitumor Effect of AZD4547 in a Fibroblast Growth Factor Receptor 2–Amplified Gastric Cancer Patient–Derived Cell Model()

BACKGROUND: FGFR2 amplification is associated with aggressive gastric cancer (GC), and targeted drugs have been developed for treatment of GC. We evaluated the antitumor activity of an FGFR inhibitor in FGFR2-amplified GC patients with peritoneal carcinomatosis. METHODS: Two GC patients with FGFR2 a...

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Detalles Bibliográficos
Autores principales: Jang, Jiryeon, Kim, Hee Kyung, Bang, Heejin, Kim, Seung Tae, Kim, Sun Young, Park, Se Hoon, Lim, Ho Yeong, Kang, Won Ki, Lee, Jeeyun, Kim, Kyoung-Mee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430153/
https://www.ncbi.nlm.nih.gov/pubmed/28501555
http://dx.doi.org/10.1016/j.tranon.2017.03.001