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A Modified Adenovirus Vector–Mediated Antibody Screening Method Identifies EphA2 as a Cancer Target()
BACKGROUND: We constructed a genetically modified adenovirus vector incorporating an IgG Fc-binding motif from staphylococcal protein A, Z33 (Adv-FZ33). Adv-FZ33 allows an antibody to redirect the vector to a target molecule on the cell surface. We attempted to search for target antigen candidates a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430157/ https://www.ncbi.nlm.nih.gov/pubmed/28505517 http://dx.doi.org/10.1016/j.tranon.2017.04.001 |