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A Modified Adenovirus Vector–Mediated Antibody Screening Method Identifies EphA2 as a Cancer Target()

BACKGROUND: We constructed a genetically modified adenovirus vector incorporating an IgG Fc-binding motif from staphylococcal protein A, Z33 (Adv-FZ33). Adv-FZ33 allows an antibody to redirect the vector to a target molecule on the cell surface. We attempted to search for target antigen candidates a...

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Detalles Bibliográficos
Autores principales: Tanaka, Toshihiro, Yamada, Hiromi, Kuroki, Masahide, Kodama, Shohta, Tamura, Kazuo, Takamatsu, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430157/
https://www.ncbi.nlm.nih.gov/pubmed/28505517
http://dx.doi.org/10.1016/j.tranon.2017.04.001