Flow virometry analysis of envelope glycoprotein conformations on individual HIV virions

HIV-1 envelope proteins (Envs) play a critical role in HIV infection. In a correct trimeric conformation, Env mediates virus–cell binding and fusion. Malfunctioning of this machinery renders virions incapable of infecting cells. Each HIV-1 virion carries 10–14 Envs, and therefore a defective Env may...

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Detalles Bibliográficos
Autores principales: Arakelyan, Anush, Fitzgerald, Wendy, King, Deborah F., Rogers, Paul, Cheeseman, Hannah M., Grivel, Jean-Charles, Shattock, Robin J., Margolis, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430429/
https://www.ncbi.nlm.nih.gov/pubmed/28424455
http://dx.doi.org/10.1038/s41598-017-00935-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430429/
https://www.ncbi.nlm.nih.gov/pubmed/28424455
http://dx.doi.org/10.1038/s41598-017-00935-w

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