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Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors

Human luteinizing hormone (LH) and chorionic gonadotropin (hCG) have been considered biologically equivalent because of their structural similarities and their binding to the same receptor; the LH/CGR. However, accumulating evidence suggest that LH/CGR differentially responds to the two hormones tri...

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Detalles Bibliográficos
Autores principales: Riccetti, Laura, Yvinec, Romain, Klett, Danièle, Gallay, Nathalie, Combarnous, Yves, Reiter, Eric, Simoni, Manuela, Casarini, Livio, Ayoub, Mohammed Akli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430435/
https://www.ncbi.nlm.nih.gov/pubmed/28424471
http://dx.doi.org/10.1038/s41598-017-01078-8