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Direct recognition of LPS drive TLR4 expressing CD8(+) T cell activation in patients with rheumatoid arthritis

Aberrant immune responses characterize autoimmune disorders like Rheumatoid Arthritis (RA) wherein lymphocytes are recognized as key players. Role of CD8(+) T cells in RA has been less defined however we found that these cells are activated in RA patients with increased expression of cytolytic granu...

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Detalles Bibliográficos
Autores principales: Tripathy, Archana, Khanna, Shweta, Padhan, Prasanta, Smita, Shuchi, Raghav, Sunil, Gupta, Bhawna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430440/
https://www.ncbi.nlm.nih.gov/pubmed/28424490
http://dx.doi.org/10.1038/s41598-017-01033-7