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Wnt-β Catenin Signaling Pathway: A Major Player in the Injury Induced Fibrosis and Dysfunction of the External Anal Sphincter

Wnt-β catenin is an important signaling pathway in the genesis of fibrosis in many organ systems. Our goal was to examine the role of Wnt pathway in the external anal sphincter (EAS) injury-related fibrosis and muscle dysfunction. New Zealand White female rabbits were subjected to surgical EAS myoto...

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Detalles Bibliográficos
Autores principales: Rajasekaran, M. Raj, Kanoo, Sadhana, Fu, Johnny, Bhargava, Valmik, Mittal, Ravinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430485/
https://www.ncbi.nlm.nih.gov/pubmed/28424479
http://dx.doi.org/10.1038/s41598-017-01131-6