Neurons Export Extracellular Vesicles Enriched in Cysteine String Protein and Misfolded Protein Cargo

The fidelity of synaptic transmission depends on the integrity of the protein machinery at the synapse. Unfolded synaptic proteins undergo refolding or degradation in order to maintain synaptic proteostasis and preserve synaptic function, and buildup of unfolded/toxic proteins leads to neuronal dysf...

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Detalles Bibliográficos
Autores principales: Deng, Jingti, Koutras, Carolina, Donnelier, Julien, Alshehri, Mana, Fotouhi, Maryam, Girard, Martine, Casha, Steve, McPherson, Peter S., Robbins, Stephen M., Braun, Janice E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430488/
https://www.ncbi.nlm.nih.gov/pubmed/28424476
http://dx.doi.org/10.1038/s41598-017-01115-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430488/
https://www.ncbi.nlm.nih.gov/pubmed/28424476
http://dx.doi.org/10.1038/s41598-017-01115-6

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