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Neurons Export Extracellular Vesicles Enriched in Cysteine String Protein and Misfolded Protein Cargo
The fidelity of synaptic transmission depends on the integrity of the protein machinery at the synapse. Unfolded synaptic proteins undergo refolding or degradation in order to maintain synaptic proteostasis and preserve synaptic function, and buildup of unfolded/toxic proteins leads to neuronal dysf...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430488/ https://www.ncbi.nlm.nih.gov/pubmed/28424476 http://dx.doi.org/10.1038/s41598-017-01115-6 |