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Mutations in the Hco-mptl-1 gene in a field-derived monepantel-resistant isolate of Haemonchus contortus()

Resistance to the anthelmintic drug monepantel (Zolvix(®)) has emerged in parasitic worms infecting sheep and goats. The mechanism of resistance in these cases is unknown. The drug targets nicotinic acetylcholine receptors belonging to the nematode-specific DEG-3 subfamily. We examined the receptor...

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Detalles Bibliográficos
Autores principales: Bagnall, Neil H., Ruffell, Angela, Raza, Ali, Elliott, Timothy P., Lamb, Jane, Hunt, Peter W., Kotze, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430491/
https://www.ncbi.nlm.nih.gov/pubmed/28501715
http://dx.doi.org/10.1016/j.ijpddr.2017.05.001