Targeting Wnt/β-Catenin Activated Cells with Dominant-Negative N-cadherin to Reduce Neointima Formation

Approximately 50% of coronary artery bypass grafts using the autologous saphenous vein fail within 10 years due to intimal thickening. This study examined whether a gene therapy approach that selectively kills Wnt/β-catenin/T cell factor (TCF) activated vascular smooth muscle cells (VSMCs) using dom...

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Detalles Bibliográficos
Autores principales: Hulin-Curtis, Sarah, Williams, Helen, Wadey, Kerry S., Sala-Newby, Graciela B., George, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430493/
https://www.ncbi.nlm.nih.gov/pubmed/28540322
http://dx.doi.org/10.1016/j.omtm.2017.04.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430493/
https://www.ncbi.nlm.nih.gov/pubmed/28540322
http://dx.doi.org/10.1016/j.omtm.2017.04.009

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