Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration

We present a novel, all-electric approach to record and to precisely control the activity of tens of individual presynaptic neurons. The method allows for parallel mapping of the efficacy of multiple synapses and of the resulting dynamics of postsynaptic neurons in a cortical culture. For the measur...

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Detalles Bibliográficos
Autores principales: Jäckel, David, Bakkum, Douglas J., Russell, Thomas L., Müller, Jan, Radivojevic, Milos, Frey, Urs, Franke, Felix, Hierlemann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430511/
https://www.ncbi.nlm.nih.gov/pubmed/28428560
http://dx.doi.org/10.1038/s41598-017-00981-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430511/
https://www.ncbi.nlm.nih.gov/pubmed/28428560
http://dx.doi.org/10.1038/s41598-017-00981-4

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