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Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration
We present a novel, all-electric approach to record and to precisely control the activity of tens of individual presynaptic neurons. The method allows for parallel mapping of the efficacy of multiple synapses and of the resulting dynamics of postsynaptic neurons in a cortical culture. For the measur...
Autores principales: | Jäckel, David, Bakkum, Douglas J., Russell, Thomas L., Müller, Jan, Radivojevic, Milos, Frey, Urs, Franke, Felix, Hierlemann, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430511/ https://www.ncbi.nlm.nih.gov/pubmed/28428560 http://dx.doi.org/10.1038/s41598-017-00981-4 |
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