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Glucocorticoids Suppress Antimicrobial Autophagy and Nitric Oxide Production and Facilitate Mycobacterial Survival in Macrophages

Chronic administration of glucocorticoids has been shown to render individuals highly susceptible to mycobacterial infection and lead to reactivation of latent bacilli. However, the effect of glucocorticoids on innate anti-mycobacterial defense, especially in macrophages remains largely unknown. Her...

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Detalles Bibliográficos
Autores principales: Wang, Jinli, Wang, Ruining, Wang, Hui, Yang, Xiaofan, Yang, Jiahui, Xiong, Wenjing, Wen, Qian, Ma, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430514/
https://www.ncbi.nlm.nih.gov/pubmed/28428627
http://dx.doi.org/10.1038/s41598-017-01174-9