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The prognostic significance of Cdc6 and Cdt1 in breast cancer

DNA replication is a critical step in cell proliferation. Overexpression of MCM2-7 genes correlated with poor prognosis in breast cancer patients. However, the roles of Cdc6 and Cdt1, which work with MCMs to regulate DNA replication, in breast cancers are largely unknown. In the present study, we ha...

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Detalles Bibliográficos
Autores principales: Mahadevappa, Ravikiran, Neves, Henrique, Yuen, Shun Ming, Bai, Yuchen, McCrudden, Cian M., Yuen, Hiu Fung, Wen, Qing, Zhang, Shu Dong, Kwok, Hang Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430515/
https://www.ncbi.nlm.nih.gov/pubmed/28428557
http://dx.doi.org/10.1038/s41598-017-00998-9