Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R

Orexigenic hormone ghrelin and anorexic hormone obestatin are encoded by the same preproghrelin gene. While it is known that ghrelin inhibits glucose-stimulated insulin secretion (GSIS), the effect of obestatin on GSIS is unclear. Ghrelin’s effect is mediated by its receptor Growth Hormone Secretago...

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Detalles Bibliográficos
Autores principales: Pradhan, Geetali, Wu, Chia-Shan, Han Lee, Jong, Kanikarla, Preeti, Guo, Shaodong, Yechoor, Vijay K., Samson, Susan L., Sun, Yuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430520/
https://www.ncbi.nlm.nih.gov/pubmed/28428639
http://dx.doi.org/10.1038/s41598-017-00888-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430520/
https://www.ncbi.nlm.nih.gov/pubmed/28428639
http://dx.doi.org/10.1038/s41598-017-00888-0

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