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Treatment of donor corneal tissue with immunomodulatory cytokines: a novel strategy to promote graft survival in high-risk corneal transplantation

Antigen-presenting cells (APCs) play an important role in transplant rejection and tolerance. In high-risk corneal transplantation, where the graft bed is inflamed and vascularized, immature APCs in the donor corneal stroma quickly mature and migrate to lymphoid tissues to sensitize host T cells. In...

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Detalles Bibliográficos
Autores principales: Tahvildari, Maryam, Emami-Naeini, Parisa, Omoto, Masahiro, Mashaghi, Alireza, Chauhan, Sunil K., Dana, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430534/
https://www.ncbi.nlm.nih.gov/pubmed/28428556
http://dx.doi.org/10.1038/s41598-017-01065-z