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Network-assisted analysis of GWAS data identifies a functionally-relevant gene module for childhood-onset asthma

The number of genetic factors associated with asthma remains limited. To identify new genes with an undetected individual effect but collectively influencing asthma risk, we conducted a network-assisted analysis that integrates outcomes of genome-wide association studies (GWAS) and protein-protein i...

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Detalles Bibliográficos
Autores principales: Liu, Y., Brossard, M., Sarnowski, C., Vaysse, A., Moffatt, M., Margaritte-Jeannin, P., Llinares-López, F., Dizier, M. H., Lathrop, M., Cookson, W., Bouzigon, E., Demenais, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430538/
https://www.ncbi.nlm.nih.gov/pubmed/28428554
http://dx.doi.org/10.1038/s41598-017-01058-y