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Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice

The strict species specificity of Human Cytomegalovirus (HCMV) has impeded our understanding of antiviral adaptive immune responses in the context of a human immune system. We have previously shown that HCMV infection of human hematopoietic progenitor cells engrafted in immune deficient mice (huNSG)...

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Detalles Bibliográficos
Autores principales: Crawford, Lindsey B., Tempel, Rebecca, Streblow, Daniel N., Kreklywich, Craig, Smith, Patricia, Picker, Louis J., Nelson, Jay A., Caposio, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430540/
https://www.ncbi.nlm.nih.gov/pubmed/28428537
http://dx.doi.org/10.1038/s41598-017-01051-5