Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop

Protein kinases are essential molecules in life and their crucial function requires tight regulation. Many kinases are regulated via phosphorylation within their activation loop. This loop is embedded in the activation segment, which additionally contains the Mg(2+) binding loop and a P + 1 loop tha...

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Detalles Bibliográficos
Autores principales: Cobbaut, Mathias, Derua, Rita, Döppler, Heike, Lou, Hua Jane, Vandoninck, Sandy, Storz, Peter, Turk, Benjamin E., Seufferlein, Thomas, Waelkens, Etienne, Janssens, Veerle, Van Lint, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430542/
https://www.ncbi.nlm.nih.gov/pubmed/28428613
http://dx.doi.org/10.1038/s41598-017-00800-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430542/
https://www.ncbi.nlm.nih.gov/pubmed/28428613
http://dx.doi.org/10.1038/s41598-017-00800-w

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