Cargando…
Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop
Protein kinases are essential molecules in life and their crucial function requires tight regulation. Many kinases are regulated via phosphorylation within their activation loop. This loop is embedded in the activation segment, which additionally contains the Mg(2+) binding loop and a P + 1 loop tha...
Autores principales: | Cobbaut, Mathias, Derua, Rita, Döppler, Heike, Lou, Hua Jane, Vandoninck, Sandy, Storz, Peter, Turk, Benjamin E., Seufferlein, Thomas, Waelkens, Etienne, Janssens, Veerle, Van Lint, Johan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430542/ https://www.ncbi.nlm.nih.gov/pubmed/28428613 http://dx.doi.org/10.1038/s41598-017-00800-w |
Ejemplares similares
-
Protein kinase D displays intrinsic Tyr autophosphorylation activity: insights into mechanism and regulation
por: Cobbaut, Mathias, et al.
Publicado: (2018) -
Function and Regulation of Protein Kinase D in Oxidative Stress: A Tale of Isoforms
por: Cobbaut, Mathias, et al.
Publicado: (2018) -
In Vitro Phosphorylation Does not Influence the Aggregation Kinetics of WT α-Synuclein in Contrast to Its Phosphorylation Mutants
por: Schreurs, Sarah, et al.
Publicado: (2014) -
Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells
por: Fleming Martinez, Alicia K., et al.
Publicado: (2021) -
The phosphorylation status of VASP at serine 322 can be predictive for aggressiveness of invasive ductal carcinoma
por: Döppler, Heike, et al.
Publicado: (2015)