Cargando…

Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine

Eubacterial ribosomal large-subunit methyltransferase H (RlmH) methylates 23S ribosomal RNA pseudouridine 1915 (Ψ1915), which lies near the ribosomal decoding center. The smallest member of the SPOUT superfamily of methyltransferases, RlmH lacks the RNA recognition domain found in larger methyltrans...

Descripción completa

Detalles Bibliográficos
Autores principales: Koh, Cha San, Madireddy, Rohini, Beane, Timothy J., Zamore, Phillip D., Korostelev, Andrei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430550/
https://www.ncbi.nlm.nih.gov/pubmed/28428565
http://dx.doi.org/10.1038/s41598-017-01186-5