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Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine
Eubacterial ribosomal large-subunit methyltransferase H (RlmH) methylates 23S ribosomal RNA pseudouridine 1915 (Ψ1915), which lies near the ribosomal decoding center. The smallest member of the SPOUT superfamily of methyltransferases, RlmH lacks the RNA recognition domain found in larger methyltrans...
Autores principales: | Koh, Cha San, Madireddy, Rohini, Beane, Timothy J., Zamore, Phillip D., Korostelev, Andrei A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430550/ https://www.ncbi.nlm.nih.gov/pubmed/28428565 http://dx.doi.org/10.1038/s41598-017-01186-5 |
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