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Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria

A main challenge in chemotherapy is to determine the in cellulo parameters modulating the drug concentration required for therapeutic action. It is absolutely urgent to understand membrane permeation and intracellular concentration of antibiotics in clinical isolates: passing the membrane barrier to...

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Detalles Bibliográficos
Autores principales: Allam, Anas, Maigre, Laure, Vergalli, Julia, Dumont, Estelle, Cinquin, Bertrand, Alves de Sousa, Rodolphe, Pajovic, Jelena, Pinet, Elizabeth, Smith, Nikaia, Herbeuval, Jean-Philippe, Réfrégiers, Matthieu, Artaud, Isabelle, Pagès, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430551/
https://www.ncbi.nlm.nih.gov/pubmed/28428543
http://dx.doi.org/10.1038/s41598-017-00945-8