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Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria
A main challenge in chemotherapy is to determine the in cellulo parameters modulating the drug concentration required for therapeutic action. It is absolutely urgent to understand membrane permeation and intracellular concentration of antibiotics in clinical isolates: passing the membrane barrier to...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430551/ https://www.ncbi.nlm.nih.gov/pubmed/28428543 http://dx.doi.org/10.1038/s41598-017-00945-8 |