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Severe hearing loss and outer hair cell death in homozygous Foxo3 knockout mice after moderate noise exposure

Noise induced hearing loss (NIHL) is a disease that affects millions of Americans. Identifying genetic pathways that influence recovery from noise exposure is an important step forward in understanding NIHL. The transcription factor Foxo3 integrates the cellular response to oxidative stress and play...

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Detalles Bibliográficos
Autores principales: Gilels, Felicia, Paquette, Stephen T., Beaulac, Holly J., Bullen, Anwen, White, Patricia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430619/
https://www.ncbi.nlm.nih.gov/pubmed/28432353
http://dx.doi.org/10.1038/s41598-017-01142-3