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Phenome-wide association study for CYP2A6 alleles: rs113288603 is associated with hearing loss symptoms in elderly smokers

To identify novel phenotypic associations related to Cytochrome P450 Family 2 Subfamily A Member 6 (CYP2A6), we investigated the human phenome in a total of 11,271 individuals. Initially, we conducted a phenome-wide association study in 3,401 nicotine-exposed elderly subjects considering 358 phenoty...

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Detalles Bibliográficos
Autores principales: Polimanti, Renato, Jensen, Kevin P., Gelernter, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430682/
https://www.ncbi.nlm.nih.gov/pubmed/28432340
http://dx.doi.org/10.1038/s41598-017-01098-4